Key result
Large animal models, including swine and sheep, are utilized for training and research in cardiovascular diseases such as aneurysms, myocardial infarction, and atrial fibrillation.
This article reviews various large animal models (swine, sheep) used for cardiovascular disease research and training, including models for aneurysms, myocardial infarction, atrial fibrillation, and transcatheter valve replacement.
Provides a consolidated resource for preclinical procedural training; leaves open the direct translation of these large animal models to.
ARTICLES DISCUSSED: Blanco-Blázquez, V. et al. Swine models of aneurysmal diseases for training and research. Journal of Visualized Experiments. (181), e63616 (2022). Constantin, I., Tăbăran, A. F. Dissection techniques and histological sampling of the heart in large animal models for cardiovascular diseases. Journal of Visualized Experiments. (184), e63809 (2022). Hao, Y. et al. Transcatheter pulmonary valve replacement from autologous pericardium with a self-expandable nitinol stent in an adult sheep model. Journal of Visualized Experiments. (184), e63661 (2022). Martínez-Falguera, D. et al. Myocardial infarction by percutaneous embolization coil deployment in a swine model. Journal of Visualized Experiments. (177), e63172 (2021). Tubeeckx, M. R. L. et al. Sterile pericarditis in aachener minipigs as a model for atrial myopathy and atrial fibrillation. Journal of Visualized Experiments. (175), e63094 (2021).
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Báez-Díaz et al. (2023) conducted a review in Cardiovascular disease. Large animal models was evaluated. Large animal models, including swine and sheep, are utilized for training and research in cardiovascular diseases such as aneurysms, myocardial infarction, and atrial fibrillation.
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