Key result
This collection discusses various large animal models of cardiovascular disease, including swine and sheep models for aneurysms, myocardial infarction, valve replacement, and atrial fibrillation.
This article discusses various large animal models used for cardiovascular disease training and translational research.
Guides preclinical training rather than clinical practice; leaves open how these large animal models translate to human cardiovascular outcomes.
ARTICLES DISCUSSED: Blanco-Blázquez, V. et al. Swine models of aneurysmal diseases for training and research. Journal of Visualized Experiments. (181), e63616 (2022). Constantin, I., Tăbăran, A. F. Dissection techniques and histological sampling of the heart in large animal models for cardiovascular diseases. Journal of Visualized Experiments. (184), e63809 (2022). Hao, Y. et al. Transcatheter pulmonary valve replacement from autologous pericardium with a self-expandable nitinol stent in an adult sheep model. Journal of Visualized Experiments. (184), e63661 (2022). Martínez-Falguera, D. et al. Myocardial infarction by percutaneous embolization coil deployment in a swine model. Journal of Visualized Experiments. (177), e63172 (2021). Tubeeckx, M. R. L. et al. Sterile pericarditis in aachener minipigs as a model for atrial myopathy and atrial fibrillation. Journal of Visualized Experiments. (175), e63094 (2021).
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Báez-Díaz et al. (2023) conducted a review in Cardiovascular disease. Large animal models was evaluated. This collection discusses various large animal models of cardiovascular disease, including swine and sheep models for aneurysms, myocardial infarction, valve replacement, and atrial fibrillation.
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