Population
Cloned voltage-dependent K+ channels expressed in human embryonic kidney cell line 293 cells
Design
Preclinical
Authors
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No immediate clinical implications for dihydropyridine use; leaves open potential effects on repolarization pending in vivo data.
Dihydropyridine calcium channel antagonists and agonists inhibit cardiac transient outward potassium channels (Kv4.3L, Kv4.2, Kv1.4) at submicromolar concentrations in vitro.
Hatano et al. (2003) studied this question.
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