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July 1, 2008The Pediatric Infectious Disease Journal

Frequent Detection of Viral Coinfection in Children Hospitalized With Acute Respiratory Tract Infection Using a Real-Time Polymerase Chain Reaction

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Why the study?

Does a 1-step real-time PCR detect viral coinfections in children hospitalized with acute respiratory tract infection?

Population

254 children admitted to the Departments of Pediatrics with acute respiratory tract infection during a…

Design

Cross-sectional

Authors

LBLinda BonzelTTTobias TenenbaumHSHorst Schroten

Discussion

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Overview

Viral coinfections occur frequently in pediatric ARTI, especially pneumonia; leaves open whether routine PCR testing improves outcomes or management.

Structured PICO

Does a 1-step real-time PCR detect viral coinfections in children hospitalized with acute respiratory tract infection?

P
Population
254 children admitted to the Departments of Pediatrics with acute respiratory tract infection (ARI) during a 10-month period
I
Intervention
1-step real-time PCR for the detection of 12 respiratory viruses (10 RNA and 2 DNA viruses)
O
Outcome
Detection of viral pathogens and viral coinfectionsurrogate

Real-time PCR frequently detects viral coinfections, particularly RSV and hBoV, in children hospitalized with acute respiratory tract infections.

Cite This Study

Bonzel et al. (2008) studied this question.

synapsesocial.com/papers/6a8fc56f4de49b62f41fcf20https://doi.org/10.1097/inf.0b013e3181694fb9
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