Why the study?
What are the characteristics of instantaneous pulmonary capillary blood flow patterns in patients with heart disease?
What are the characteristics of instantaneous pulmonary capillary blood flow patterns in patients with heart disease?
Pulmonary capillary blood flow patterns become less pulsatile and more uniform in patients with heart disease complicated by pulmonary hypertension, right ventricular failure, or low cardiac output.
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Uniform pulmonary capillary flow may signal pulmonary hypertension or RV failure; leaves open its diagnostic or prognostic value in heart disease.
The instantaneous pattern of pulmonary capillary blood flow was recorded by the nitrous oxide-body-plethysmograph method in 36 patients with heart disease. It was found to be abnormal in the presence of significant pulmonary arterial or pulmonary venous hypertension. Tachycardia, a low cardiac output, and right ventricular failure also contributed to converting a normally pulsatile capillary blood flow pattern to a more uniform one.
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Karatzas et al. (1970) studied this question.
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