What does this research mean for the field?

Although positively associated with pregnancy, Anti-Müllerian hormone (AMH) has poor predictive value for pregnancy in women with or without assisted reproductive technology. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate whether pre-pregnancy anti-Müllerian hormone (AMH) levels predict pregnancy with or without assisted reproductive technology (ART).

August 27, 2026Taiwanese Journal of Obstetrics and GynecologyOpen Access

Anti-Müllerian hormone is a poor predictor of pregnancy with and without assisted reproductive technology: A population-based register study of 43,269 Danish women

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Authors

MGMaja GeorgsenHvidovre Hospital FKFreja Rueholm KlokHvidovre Hospital LPLisbeth Prætorius

Discussion

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Implication

Population-based register study reveals anti-Müllerian hormone poorly predicts pregnancy in reproductive-age women, indicating limited clinical utility for forecasting natural or assisted conception.

Key Points

To evaluate whether pre-pregnancy anti-Müllerian hormone (AMH) levels predict pregnancy with or without assisted reproductive technology (ART).
Conducted a population-based register study of 43,269 women aged 18–50 years in the Copenhagen Capital Region with baseline AMH measurements between 2010 and 2022 linked to national health registers.
Tracked confirmed pregnancies via first-trimester biochemical screening (PAPP-A and free β-hCG) over a 3-year follow-up period across ART status and maternal age strata.
Evaluated associations and predictive performance using multivariable regression and receiver operating characteristic (ROC) curve analyses.
Of 43,269 women, 27,395 achieved confirmed pregnancy within the 3-year follow-up period, while 15,874 did not.
AMH showed an overall positive association with pregnancy after adjustment for age, fertility treatment, and comorbidities, but exhibited poor predictive performance (AUC 0.50–0.69).
Predictive accuracy was highest in women older than 40 years conceiving without assisted reproductive technology.

Cite This Study

Georgsen et al. (2026) studied this question.

synapsesocial.com/papers/6a8fea3310c91c1e9262252e https://doi.org/10.1016/j.tjog.2026.07.002

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Anti-Müllerian hormone is a poor predictor of pregnancy with and without assisted reproductive technology: A population-based register study of 43,269 Danish women

Discussion

Member takes

Implication

Key Points

Cite This Study

Anti-Müllerian hormone is a poor predictor of pregnancy with and without assisted reproductive technology: A population-based register study of 43,269 Danish women

Discussion

Member takes

Implication

Key Points

Cite This Study

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