Why the study?
Does administration of methoxamine during cervical epidural anesthesia induce coronary artery spasm with ventricular tachycardia in a patient with no prior history of myocardial ischemia?
Does administration of methoxamine during cervical epidural anesthesia induce coronary artery spasm with ventricular tachycardia in a patient with no prior history of myocardial ischemia?
Methoxamine administration during cervical epidural anesthesia may induce coronary artery spasm and ventricular tachycardia even in patients without prior myocardial ischemia.
Answers are grounded in this paper and cite their sources.
May signal risk with methoxamine in cervical epidural anesthesia; hypothesis-generating case leaves causality and generalizability open.
Coronary artery spasm occurred during thoracotomy under cervical epidural anesthesia in a 60-year-old male patient who had no prior history of myocardial ischemia. It is most likely that the administration of methoxamine induced the spasm. Hypotension and venodilatation induced by the epidural anesthesia and increased vagal tone might also contribute to the spasm.
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Mizuyama et al. (1993) studied this question.
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