Key result
A 27-year-old pregnant woman with Eisenmenger syndrome was successfully managed with medical therapy and elective caesarean section at 34 weeks, resulting in a healthy mother and baby.
Why the study?
Eisenmenger syndrome during pregnancy carries high maternal mortality, but rare cases achieve successful delivery and favorable outcomes.
Does multidisciplinary management including pulmonary vasodilators and planned caesarean section improve maternal and fetal outcomes in a pregnant woman with Eisenmenger syndrome?
Case Report (n=1)
No
Does multidisciplinary management including pulmonary vasodilators and planned caesarean section improve maternal and fetal outcomes in a pregnant woman with Eisenmenger syndrome?
Despite the extremely high maternal mortality associated with Eisenmenger syndrome, successful pregnancy outcomes are possible with multidisciplinary care, medical therapy including pulmonary vasodilators, and planned delivery.
Answers are grounded in this paper and cite their sources.
Pregnancy discouraged in Eisenmenger syndrome due to high mortality; novel Level 5 data leaves optimal peripartum strategies open.
Eisenmenger syndrome is a very rare heart disease in pregnant women. Eisenmenger syndrome is defined as pulmonary hypertension resulting from an uncorrected left to right shunt of a VSD, ASD or patent ductus arteriosus (PDA), with subsequent shunt reversal and cyanosis. Pulmonary hypertension is the prognosis index. The high mortality risk (25-30%) is associated with pregnancy and the peripartum period due to cardiovascular collapse. Pregnancy should be discouraged and reliable contraception, preferably permanent sterilization, advised because of the extreme risk associated with pregnancy. Depo-Provera or progesterone implants are nonsurgical alternatives. Even first-trimester termination is associated with a maternal mortality rate of 5-10%. However, despite all the risks, a few patients deliver successfully with a good maternal and neonatal outcome. We presented a 27-year-old booked G1P0+0 admitted at 34 weeks gestation with Eisenmenger syndrome. She was treated medically during pregnancy, underwent elective caesarean section at 34 weeks of gestation delivered a baby and was subsequently discharged on the 15th postoperative day without any serious complications.
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Tuhin S. Roy (2022) conducted a case report in Eisenmenger syndrome in pregnancy (n=1). Multidisciplinary medical management and elective caesarean section was evaluated on Maternal and neonatal outcome. A 27-year-old pregnant woman with Eisenmenger syndrome was successfully managed with medical therapy and elective caesarean section at 34 weeks, resulting in a healthy mother and baby.
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