Key result
Dextran sulphate demonstrates heparin-like anticoagulant activity mediated by plasma protein interactions.
Why the study?
The biological behaviour and heparin-like properties of new synthetic sulphuric ester polysaccharides such as dextran sulphate require characterization.
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K. W. Walton (1952) studied this question. Dextran sulphate was evaluated. Dextran sulphate is a new synthetic anticoagulant whose heparin-like activity is likely mediated by the interaction of its sulphuric esters with plasma proteins.
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