Why the study?
What is the incidence of infection and other complications in patients implanted with Jarvik-7 and Jarvik 7-70 total artificial hearts?
What is the incidence of infection and other complications in patients implanted with Jarvik-7 and Jarvik 7-70 total artificial hearts?
Infections, primarily caused by Staphylococcus epidermidis and Pseudomonas aeruginosa, occur in nearly 30% of patients implanted with Jarvik-7 total artificial hearts.
Answers are grounded in this paper and cite their sources.
Infection incidence near 30% in TAH patients warrants surveillance; leaves optimal pathogen-specific prevention open.
A variety of prosthetic blood pumps are currently undergoing experimental development or are available for clinical use. The Jarvik-7 and Jarvik 7-70 (Symbion-7 and Symbion 7-70) total artificial hearts (TAH) have been used worldwide both experimentally and for clinical mechanical circulatory support. Of the 190 patients implanted with these devices, 133 went on to cardiac transplantation and 68 of the transplanted patients are alive. Complications associated with the use of the TAH have included postoperative hemorrhage, thrombosis with thromboembolism and infection. The incidence of infection in the patients implanted with the TAH has declined-significantly since initial clinical use and is now near 30%. Staphylococcus epidermidis and Pseudomonas aeruginosa are the most commonly pathogens isolated from these devices.
No takes yet. Share an insight, caveat, or question.
G. Leonard Burns (1993) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: