A practical guide on how to handle patients with bleeding events while on oral antithrombotic treatment
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Key result
Restarting antithrombotic treatment is generally advised after a bleeding event, except for patients suffering from a lobar cerebral haemorrhage, though decisions require multidisciplinary evaluation.
Population
Patients experiencing bleeding events while on oral antithrombotic therapy
Design
Review
Authors
Discussion
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Member takes
Implication
Informs post-bleed antithrombotic decisions via multidisciplinary input; leaves open RCTs to refine lobar ICH exceptions.
Structured PICO
P
Population
Patients experiencing bleeding events while on oral antithrombotic therapy (oral anticoagulation or antiplatelet therapy)
I
Intervention
Management strategies for antithrombotic therapy (continuation, interruption, reversal, and resumption)
This review provides a practical, guideline-based framework for the complex clinical dilemma of balancing bleeding and thrombotic risks when managing antithrombotic therapy during and after bleeding events.
Limitations
- The available guidance is primarily based on observational cohort studies with a high risk of confounding.
Cite This Study
Gimbel et al. (2018) conducted a review in Bleeding events while on oral antithrombotic treatment. Management of antithrombotic therapy after bleeding was evaluated. Restarting antithrombotic treatment is generally advised after a bleeding event, except for patients suffering from a lobar cerebral haemorrhage, though decisions require multidisciplinary evaluation.
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