What question did this study set out to answer?

Evaluate the clinical efficacy, safety, and patient tolerance of cefoxitin in treating acute respiratory tract and other bacterial infections.

January 1, 1979Clinical Infectious Diseases

Clinical Evaluation of Cefoxitin in the Treatment of Respiratory Tract and Other Acute Bacterial Infections

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Authors

MWMelvin P. WeinsteinRutgers, The State University of New Jersey TETheodore C. EickhoffConference Board

Discussion

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Implication

Clinical trial demonstrates high clinical efficacy and safety of cefoxitin in acute respiratory infections, indicating its viability as an effective intravenous antibacterial therapy.

Key Points

Evaluate the clinical efficacy, safety, and patient tolerance of cefoxitin in treating acute respiratory tract and other bacterial infections.
Conducted a clinical trial involving N=26 clinically evaluable patients, including 21 individuals diagnosed with acute respiratory tract infections, receiving intravenous cefoxitin.
Monitored clinical response to therapy alongside laboratory measures of renal function, hematologic parameters, hepatic enzymes, and local infusion-site tolerance.
Satisfactory therapeutic response was achieved in 25 of 26 patients overall, including 20 of 21 patients with acute respiratory tract infections.
No systemic adverse reactions or renal/hematologic toxicities were observed, although 2 patients exhibited mild, drug-related elevations in hepatic enzymes.
Approximately one-third of patients experienced minor local injection-site irritation, with 1 confirmed case of true thrombophlebitis.

Cite This Study

Weinstein et al. (1979) studied this question.

synapsesocial.com/papers/6a90126eed78fcc1e60d2c80 https://doi.org/10.1093/clinids/1.1.158

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Implication

Clinical trial demonstrates high clinical efficacy and safety of cefoxitin in acute respiratory infections, indicating its viability as an effective intravenous antibacterial therapy.

Clinical Evaluation of Cefoxitin in the Treatment of Respiratory Tract and Other Acute Bacterial Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical Evaluation of Cefoxitin in the Treatment of Respiratory Tract and Other Acute Bacterial Infections

Discussion

Member takes

Implication

Key Points

Cite This Study

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