Inorganic salts provide thermal stabilization to various viruses against moderate heat, though the exact mechanism involving cations or anions remains unclear.
May support salt-based virus stabilization in veterinary settings; leaves open mechanisms and clinical translation.
Inorganic salts protect some viruses against the inactivating effect of moderate heat. This thermal stabilization has been reported by Wallis and Melnick (7) for poliovirus, by Wallis et al. (6) for vaccinia, Herpes simplex, and adenovirus, and by Rapp et al. (5) for measles virus. The nature of the role played by the salts in stabilizing the viruses is not yet understood. Early reports ascribe the activity to the cations. The report of Wallis et al. (9) indicates that the stabilization of poliovirus cannot be generalized to cations or anions. Rapp et al. (5) demonstrated that the sulfate anion stabilizes measles virus.
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S. R. Hopkins (1967) studied this question.
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