Key result
Treatment with corticosteroids and colchicine resulted in the resolution of pericardial effusion and recovery of ventricular function in two patients with COVID-19-associated pericarditis.
Why the study?
COVID-19 causes high-mortality complications where respiratory manifestations are most common and cardiovascular complications are among the most severe.
Case Report (n=2)
No
Pericarditis with severe ventricular dysfunction can complicate COVID-19 infection and may be successfully treated with corticosteroids and colchicine.
May support corticosteroids plus colchicine in COVID-19 pericarditis; hypothesis-generating and leaves open need for controlled trials.
COVID-19 infection is responsible for many complications, which can lead to a high risk of mortality. Respiratory manifestations are the most encountered, while that cardiovascular complications are classified as the most severe. We report two cases of COVID-19 infection complicated by pericarditis. In the absence of other etiology of pericarditis, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was considered as the behind cause. The treatment in these two cases was corticosteroids with colchicine, with good outcomes. In the presence of any cardiovascular symptoms, pericarditis related to COVID-19 should be suspected, in order to act swiftly and avoid complications as well as contamination.
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Mir et al. (2022) conducted a case report in COVID-19 infection complicated by pericarditis (n=2). Corticosteroids and colchicine was evaluated on Resolution of pericardial effusion and recovery of ventricular function. Treatment with corticosteroids and colchicine resulted in the resolution of pericardial effusion and recovery of ventricular function in two patients with COVID-19-associated pericarditis.
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