Answers are grounded in this paper and cite their sources.
Conditions are described for the large scale production of mouse interferons from Ehrlich ascites tumour cells cultured as monolayers in roller bottles. With the procedure reported here, we have used 50 to 65 600 cm(2) roller bottles to produce routinely 2 X 10(9) to 3 X 10(9) International units of crude mouse interferon/week with a specific activity of 1 X 10(6) to 1.5 X 10(6) units/mg protein.
No takes yet. Share an insight, caveat, or question.
Taira et al. (1980) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: