Why the study?
Is the threshold concentration for ADP-induced platelet aggregation altered in patients with ischemic heart disease or peripheral thromboatherosclerosis compared to normal controls?
Population
142 individuals, comprising 30 patients with ischemic heart disease, 22 patients with peripheral…
Comparison
In vitro assessment of ADP-induced platelet… vs Normal controls
Design
Case-control
Authors
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Increased ADP sensitivity in IHD and PTA should not change practice; hypothesis-generating for prospective studies on platelet reactivity.
Is the threshold concentration for ADP-induced platelet aggregation altered in patients with ischemic heart disease or peripheral thromboatherosclerosis compared to normal controls?
Patients with ischemic heart disease and peripheral thromboatherosclerosis exhibit increased in vitro platelet sensitivity to ADP compared to healthy controls.
Gormsen et al. (1977) studied this question.
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