Key result
Neostigmine usage was associated with increased diagnoses of atelectasis, and unwarranted usage was independently associated with pulmonary edema and reintubation in 3,000 postoperative patients.
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Neuromuscular blockade reversal should be guided by quantitative monitoring rather than administered routinely to avoid adverse respiratory outcomes.
Meyer et al. (2017) conducted a letter in Postoperative patients (n=3,000). Neostigmine usage was evaluated on Atelectasis, pulmonary edema, and reintubation. Neostigmine usage was associated with increased diagnoses of atelectasis, and unwarranted usage was independently associated with pulmonary edema and reintubation in 3,000 postoperative patients.
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