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January 1, 2018Indian Journal of AnaesthesiaOpen Access

Response to comments on “Reversal agents: Do we need to administer with neuromuscular monitoring”

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Key result

The authors clarify their study was observational and reiterate that objective neuromuscular monitoring should be mandatory to avoid residual neuromuscular blockade effects or shortcomings of neostigmine.

Design

Other

Authors

NKNikhil KothariSGShilpa GoyalDCDeepak Chaudhary

Discussion

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Overview

May support mandatory objective monitoring to limit residual blockade; leaves open confirmation via randomized trials.

PICO

P
Population
Neuromuscular blockade reversal
E
Exposure / Comparator
Objective neuromuscular monitoring vs Subjective monitoring
O
Primary Outcome
Suitable time for extubation

The authors defend their observational study design, arguing that objective neuromuscular monitoring should be mandatory to avoid residual neuromuscular blockade effects.

Limitations

  • Patients with surgery duration exceeding 2 hours were excluded
  • Observational study design

Cite This Study

Kothari et al. (2018) conducted a letter in Neuromuscular blockade reversal. Objective neuromuscular monitoring vs. Subjective monitoring was evaluated on Suitable time for extubation. The authors clarify their study was observational and reiterate that objective neuromuscular monitoring should be mandatory to avoid residual neuromuscular blockade effects or shortcomings of neostigmine.

synapsesocial.com/papers/6a95d98a61ac54ca9cbadebahttps://doi.org/10.4103/ija.ija_237_18
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Should Neuromuscular Blocking Agents Always Be Reversed?2017 · 1 citations
  2. 2Comments on Published Article: A valuable resource2018
  3. 3Monitoring and Pharmacologic Reversal of a Nondepolarizing Neuromuscular Blockade Should Be Routine2010 · 39 citations
  4. 4Neuromuscular Monitoring as the Art of Probability2017 · 2 citations
  5. 5Not just monitoring; a strategy for managing neuromuscular blockade2015 · 33 citations