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Presentation of unknown primary cancer with metastatic liver disease—management and natural history. R. A. Nesbit, in. H. N. Tattersall, R. in. Fox and R. L. Woods, Aust. N.Z. J. med., 1981, 11, pp. 16–19. Initial blind liver biopsy established a histological diagnosis of metastatic cancer in 27 out of 34 patients who presented with clinical signs of liver metastases and no obvious primary tumour. Twenty-two of the patients had meta static adenocarcmoma, and a primary tumour site was identified before death in only four patients
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Nesbit et al. (1981) studied this question.
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