Key result
Management of sedation in a patient with prolonged long-QT syndrome was described, highlighting the need for careful selection of sedation medications to avoid precipitating arrhythmias.
Case Report (n=1)
This case report and review discusses the management and safety of commonly utilized sedation medications in patients with prolonged long-QT syndrome.
Alerts clinicians to sedation risks in long-QT syndrome; leaves open need for prospective data before practice change.
Prolonged QT syndrome is the most common genetic arrhythmia syndrome, and the majority of patients are undiagnosed. The syndrome is characterized by abnormally long ventricular repolarization (QT interval) on electrocardiogram, which may manifest as syncopal episodes, arrhythmias, or sudden death. Arrhythmias may be precipitated by stress or medications. There are few randomized controlled trials examining the safety of typical sedation medications in the patient with prolonged long-QT syndrome. This case describes the management of sedation in a patient with prolonged long-QT syndrome and then reviews the current literature regarding commonly utilized sedation medications.
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Mikesell et al. (2011) conducted a case report in Prolonged long-QT syndrome (n=1). Sedation medications was evaluated. Management of sedation in a patient with prolonged long-QT syndrome was described, highlighting the need for careful selection of sedation medications to avoid precipitating arrhythmias.
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