Exercise alters molecular profiles of inflammation and substrate metabolism in human white adipose tissue

This is the authors' abstract. We don't add key points for this paper.

This is the first study to utilize a multiomic (RNAseq, proteomics, and phosphoproteomics) approach to investigate molecular adaptations in WAT after a short-term intervention in sedentary overweight women. We show that supervised aerobic training reduces molecular markers of inflammation and proteins regulating ECM and increases abundance of transcripts and proteins involved in lipolysis and fatty acid re-esterification, indicating that molecular adaptations in WAT occur independent of alterations in body weight or fat mass.