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June 7, 2015DiabetesOpen Access

Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations

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Why the study?

Does exercise training induce beiging and metabolic adaptations in white adipose tissue?

Population

Human and rodent models

Comparison

Regular physical activity and exercise training vs Sedentary state

Design

Review

Authors

KSKristin I. StanfordRMRoeland J.W. MiddelbeekLGLaurie J. Goodyear

Discussion

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Overview

Exercise effects on WAT beiging and mitochondria extend mechanistic insights; leaves open their role in diabetes management.

Structured PICO

Does exercise training induce beiging and metabolic adaptations in white adipose tissue?

P
Population
Human and rodent models
I
Intervention
Regular physical activity and exercise training
C
Comparator
Sedentary state
O
Outcome
Adaptations to white adipose tissue (mitochondrial function, beiging, adipokine regulation, metabolic effects)surrogate

Exercise training induces profound metabolic adaptations in white adipose tissue, including beiging and altered adipokine profiles, which contribute to improved systemic metabolic health.

Cite This Study

Stanford et al. (2015) studied this question.

synapsesocial.com/papers/6a70165af44fa9f079dd9d74https://doi.org/10.2337/db15-0227
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of exercise on brown and beige adipocytes2018 · 94 citations
  2. 2Exercise-induced adaptations to white and brown adipose tissue2018 · 121 citations
  3. 3Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue2019 · 116 citations
  4. 4Exercise-induced regulation of adipose tissue2023 · 29 citations
  5. 5Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix2023 · 57 citations