Key result
Eleven days of wheel running in male mice caused profound inguinal white adipose tissue remodeling, including decreased extracellular matrix deposition and increased vascularization and innervation.
Why the study?
The mechanisms underlying the beneficial effects of exercise training on metabolic health via inguinal white adipose tissue are not fully understood.
Population
Male mice
Comparison
11 days of wheel running
Follow-up
11 days
Authors
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iWAT remodeling may mediate exercise benefits; leaves open human translation and causality.
Nigro et al. (2023) studied this question. Exercise training (wheel running) was evaluated on Inguinal white adipose tissue (iWAT) remodeling. Eleven days of wheel running in male mice caused profound inguinal white adipose tissue remodeling, including decreased extracellular matrix deposition and increased vascularization and innervation.
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