Key result
Obesity in young adults was associated with worse cardiovascular parameters during cardiopulmonary exercise testing, including lower relative oxygen pulse on maximum load (60% vs. 72%, p=0.004).
Why the study?
Obesity is an independent risk factor for cardiovascular disease, making early detection of cardiovascular dysfunction among young adults an important issue.
Does cardiopulmonary exercise testing detect cardiovascular dysfunction in young obese adults compared to non-obese adults?
Cross-Sectional (n=84)
Does cardiopulmonary exercise testing detect cardiovascular dysfunction in young obese adults compared to non-obese adults?
Cardiopulmonary exercise testing reveals significant subclinical cardiovascular impairments in young obese adults, highlighting its utility for early detection of cardiovascular dysfunction.
CPET may aid early cardiovascular assessment in young obese adults; leaves open routine use pending higher-level evidence.
BACKGROUND: Obesity is an independent risk factor for cardiovascular disease. In this regard, the early detection of cardio-vascular disfunction among young adults is an important issue. This problem can be solved by the cardiopulmonary exercise testing. AIM: The aim of this study is to determine the applicability of cardiopulmonary exercise testing to assess the functional cardiovascular state in young and obese adults. MATERIALS AND METHODS: 84 young participants (18–44 years), 39% men, underwent a comprehensive examination including anthropometry, spirometry and cardiopulmonary exercise testing using a graded protocol in the period 2021–2022. Four groups of cardiopulmonary exercise testing indicators were assessed: metabolic, cardiovascular, ventilatory and pulmonary gas exchange parameters. RESULTS: 35 participants (42%) were obese, 36 participants (43%) were smokers. The obesity had a negative impact on cardiovascular parameters of cardiopulmonary exercise testing: relative oxygen pulse on maximum load (60% vs. 72%, p = 0.004), heart rate on maximum load (86% vs. 90%, p = 0.024), maximum systolic blood pressure (181 mmHg vs. 156 mmHg, p 0.001) and maximum diastolic blood pressure (92 mmHg vs. 83 mmHg, p = 0.040). CONCLUSIONS: Cardiopulmonary exercise testing, especially assessing cardiovascular parameters, in young adults is in high practical interest for the functional cardiovascular status examination of individuals with obesity, smokers, and, particularly, in the case of their combination.
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Kelekhsaev et al. (2024) conducted a cross-sectional in Obesity (n=84). Obesity vs. Non-obese participants was evaluated on Relative oxygen pulse on maximum load (p=0.004). Obesity in young adults was associated with worse cardiovascular parameters during cardiopulmonary exercise testing, including lower relative oxygen pulse on maximum load (60% vs. 72%, p=0.004).
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