Key result
Decreasing coiling porosity from 0.89 to 0.79 reduced maximum Oscillatory Shear Index by up to 75% in simulated male patients and 45% in female patients.
Why the study?
The formation and progression of cerebral aneurysms are closely linked to hemodynamic factors, prompting investigation into blood hemodynamic effects on internal carotid artery aneurysms.
Does changing coiling porosity and blood hematocrit affect the OSI and WSS in a computational model of a cerebral aneurysm?
Does changing coiling porosity and blood hematocrit affect the OSI and WSS in a computational model of a cerebral aneurysm?
Computational fluid dynamics modeling demonstrates that lower coiling porosity significantly reduces the Oscillatory Shear Index in cerebral aneurysms, with a more pronounced effect in models simulating male hematocrit levels.
Hemodynamic CFD modeling of ICA aneurysms may refine rupture risk assessment; leaves open prospective clinical validation.
The formation and progress of cerebral aneurysm is highly associated with hemodynamic factors and blood flow feature. In this study, comprehensive efforts are done to investigate the blood hemodynamic effects on the creation and growth of the Internal Carotid Artery. The computational fluid dynamic method is used for the visualization of the bloodstream inside the aneurysm. Transitional, non-Newtonian and incompressible conditions are considered for solving the Navier-Stokes equation to achieve the high-risk region on the aneurysm wall. OSI and WSS of the aneurysm wall are compared within different blood flow stages. The effects of blood viscosity and coiling treatment on these factors are presented in this work. Our study shows that in male patients (HCT = 0.45), changing the porosity of coiling from 0.89 with 0.79 would decreases maximum OSI up to 75% (in maximum acceleration). However, this effect is limited to about 45% for female patients (HCT = 0.35).
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Sheidani et al. (2022) studied Cerebral aneurysm. Coiling porosity reduction (0.89 to 0.79) vs. Higher coiling porosity (0.89) was evaluated on Maximum Oscillatory Shear Index (OSI). Decreasing coiling porosity from 0.89 to 0.79 reduced maximum Oscillatory Shear Index by up to 75% in simulated male patients and 45% in female patients.
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