Key result
Computational modeling links average wall shear stress above 0.6 to increased cerebral aneurysm rupture risk.
Why the study?
Irregular bloodstream and circulatory flow patterns are a key contributor to stroke and high mortality, prompting evaluation of flow patterns inside cerebral aneurysms to detect hemorrhage risk.
Computational fluid dynamics modeling demonstrates that increased blood flow velocity and viscosity elevate wall shear stress, thereby increasing the risk of cerebral aneurysm rupture.
Warrants no change to clinical aneurysm management; leaves open human validation of CFD-derived wall shear stress thresholds.
In recent decades, cardiovascular disease and stroke are recognized as the most important reason for the high death rate. Irregular bloodstream and the circulatory system are the main reason for this issue. In this paper, Computational Fluid dynamic method is employed to study the impacts of the flow pattern inside the cerebral aneurysm for detection of the hemorrhage of the aneurysm. To achieve a reliable outcome, blood flow is considered as a non-Newtonian fluid with a power-law model. In this study, the influence of the blood viscosity and velocity on the pressure distribution and average wall shear stress (AWSS) are comprehensively studied. Moreover, the flow pattern inside the aneurysm is investigated to obtain the high-risk regions for the rupture of the aneurysm. Our results indicate that the wall shear stress (WSS) increases with increasing blood flow velocity. Furthermore, the risk of aneurysm rupture is considerably increased when the AWSS increases more than 0.6. Indeed, the blood flow with high viscosity expands the high-risk region on the wall of the aneurysm. Blood flow indicates that the angle of the incoming bloodstream is substantially effective in the high-risk region on the aneurysm wall. The augmentation of the blood velocity and vortices considerably increases the risk of hemorrhage of the aneurysm.
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Shen et al. (2021) studied Cerebral aneurysm. Blood flow characteristics (viscosity, velocity, angle) was evaluated on Pressure distribution, average wall shear stress (AWSS), and high-risk regions for rupture. Computational fluid dynamics modeling demonstrated that the risk of cerebral aneurysm rupture is considerably increased when average wall shear stress exceeds 0.6.
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