Why the study?
Does progressive mechanical umbilical vein compression alter blood flow patterns through the aortic isthmus in fetal lambs?
Population
Seven exteriorized fetal lambs
Comparison
Progressive increase in resistance to blood flow… vs Baseline measurements prior to compression
Design
Preclinical
Authors
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Aortic isthmus Doppler may indicate umbilical flow status in fetal models; leaves open human validation.
Does progressive mechanical umbilical vein compression alter blood flow patterns through the aortic isthmus in fetal lambs?
Variations in Doppler blood flow velocity waveforms and integrals of the aortic isthmus can serve as a sensitive indicator of the state of the umbilical circulation.
Bonnin et al. (1993) studied this question.
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