What question did this study set out to answer?

To determine whether Doppler interrogation of the fetal aortic isthmus can detect early blood flow redistribution and assess hemodynamic responses to maternal hyperoxygenation in growth-restricted fetuses.

October 1, 1999Ultrasound in Obstetrics and Gynecology

Central arterial hemodynamics in small‐for‐gestational‐age fetuses before and during maternal hyperoxygenation: a Doppler velocimetric study with particular attention to the aortic isthmus

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To determine whether Doppler interrogation of the fetal aortic isthmus can detect early blood flow redistribution and assess hemodynamic responses to maternal hyperoxygenation in growth-restricted fetuses.
Evaluated 25 singleton fetuses with estimated fetal weight below -2 standard deviations of the gestational age mean between 27 and 38 weeks of gestation (median 34 weeks).
Recorded Doppler velocity waveforms from the mitral valve, aortic valve, middle cerebral artery, aortic isthmus, and umbilical artery before and during maternal inhalation of 100% oxygen.
Nine fetuses demonstrated absent or reversed end-diastolic velocity in the aortic isthmus while forward flow remained present in the umbilical artery.
Maternal hyperoxygenation induced an increase in the middle cerebral artery pulsatility index and a decrease in the aortic isthmus pulsatility index, whereas other interrogated vascular sites showed no changes.

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Implication

Doppler ultrasound study reveals maternal hyperoxygenation alters aortic isthmus hemodynamics in small-for-gestational-age fetuses, suggesting reversal of brain-sparing blood redistribution.

Cite This Study

Brantberg et al. (1999) studied this question.

synapsesocial.com/papers/6a7354852a8e306aa0c678ba https://doi.org/10.1046/j.1469-0705.1999.14040237.x

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Implication

Doppler ultrasound study reveals maternal hyperoxygenation alters aortic isthmus hemodynamics in small-for-gestational-age fetuses, suggesting reversal of brain-sparing blood redistribution.

Central arterial hemodynamics in small‐for‐gestational‐age fetuses before and during maternal hyperoxygenation: a Doppler velocimetric study with particular attention to the aortic isthmus

Key Points

Discussion

Implication

Cite This Study

Central arterial hemodynamics in small‐for‐gestational‐age fetuses before and during maternal hyperoxygenation: a Doppler velocimetric study with particular attention to the aortic isthmus

Key Points

Discussion

Implication

Cite This Study

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