Answers are grounded in this paper and cite their sources.
B cell development is often portrayed as a series of decision points that expand an antigen-reactive cell to a clone producing a single antibody. This is hardly the case: B cell development is dependent on a series of error-prone, random rearrangement events that through ongoing diversification
No takes yet. Share an insight, caveat, or question.
Nemazee et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: