Key result
Factory default pulse durations of 0.45 or 0.5 ms exceeded acute chronaxie by a factor of two, demonstrating suboptimal pacing efficiency and excessive battery drain.
Why the study?
Does programming pulse duration to chronaxie improve pacing efficiency compared to factory default settings in patients with pacing leads?
Population
229 patients with 325 acutely implanted pacing leads (101 atrial and 224 ventricular, all passive fixation)
Comparison
Calculation of strength-duration curves to… vs Factory default pulse durations
Design
Cohort
Follow-up
acute (at implantation)
Authors
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Default settings may accelerate battery depletion; leaves open whether chronaxie-matched programming extends device longevity in trials.
Cross-Sectional (n=229)
Does programming pulse duration to chronaxie improve pacing efficiency compared to factory default settings in patients with pacing leads?
p-value: p=<0.001
Factory default pacemaker pulse durations significantly exceed acute chronaxie, suggesting that programming pulse duration to chronaxie could optimize battery longevity.
Coates et al. (2000) conducted a cross-sectional in Pacemaker implantation (n=229). Acutely implanted pacing leads was evaluated on Chronaxie and rheobase for atrial and ventricular leads (p=<0.001). Factory default pulse durations of 0.45 or 0.5 ms exceeded acute chronaxie by a factor of two, demonstrating suboptimal pacing efficiency and excessive battery drain.
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