Key result
Prior outpatient use of statins (OR 0.54; 95% CI 0.42-0.70) and ACE inhibitors (OR 0.80; 95% CI 0.68-0.89) was associated with decreased 30-day mortality in patients hospitalized with pneumonia.
Why the study?
Does outpatient use of statins and ACE inhibitors reduce 30-day mortality in older adults hospitalized with community-acquired pneumonia?
Population
8,652 subjects aged ≥65 years hospitalized with community-acquired pneumonia, with ≥1 year of prior Veterans…
Comparison
Outpatient use of statins and/or… vs Non-use of statins and/or ACE inhibitors prior…
Design
Cohort
Follow-up
30 days
Authors
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Should not yet change prescribing in pneumonia; leaves open a protective role pending randomized confirmation.
Cohort (n=8,652)
Yes
Does outpatient use of statins and ACE inhibitors reduce 30-day mortality in older adults hospitalized with community-acquired pneumonia?
Odds Ratio: 0.54 (95% CI 0.42–0.7)
Outpatient use of statins and ACE inhibitors prior to admission is associated with significantly decreased 30-day mortality in older adults hospitalized with community-acquired pneumonia.
Mortensen et al. (2007) conducted a cohort in community-acquired pneumonia (n=8,652). Statins and ACE inhibitors vs. Non-use was evaluated on 30-day mortality (OR 0.54, 95% CI 0.42-0.70). Prior outpatient use of statins (OR 0.54; 95% CI 0.42-0.70) and ACE inhibitors (OR 0.80; 95% CI 0.68-0.89) was associated with decreased 30-day mortality in patients hospitalized with pneumonia.
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