Population
Rabbit blood platelets (citrated platelet-rich plasma)
Design
Preclinical
Authors
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Hypothesis-generating for platelet activation mechanisms; leaves open translation to human hemostasis or antithrombotic targets.
Demonstrates that tendon extract initiates platelet aggregation via a two-step process involving the release of ADP from platelets, relevant to in vivo platelet plug formation.
Torstein Hovig (1963) studied this question.
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