Why the study?
Does mitral valve replacement with the University of Cape Town lenticular mitral valve prosthesis improve clinical outcomes in patients with severe mitral valve disease?
Population
122 patients with severe mitral valve disease and severe or total disability.
Design
Case_series
Follow-up
up to 7 years
Authors
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High mortality warrants caution; case report data leave open the modified prosthesis's role in severe mitral disease.
Does mitral valve replacement with the University of Cape Town lenticular mitral valve prosthesis improve clinical outcomes in patients with severe mitral valve disease?
The University of Cape Town mitral valve prosthesis provided significant clinical improvement in survivors but was associated with high mortality and systemic embolism, which was mitigated by modifying the valve seat.
Schrire et al. (1970) studied this question.
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