Key result
Among 731 children with acute diarrhea in Nepal, 23.3% tested positive for rotavirus, of which 23.0% were identified as the emerging G12 strain.
Cross-Sectional (n=731)
No
The study confirms a high prevalence (23%) of emerging G12 rotavirus strains in Nepal, highlighting the need for continued surveillance to ensure current vaccines remain effective.
May warrant expanded rotavirus strain surveillance in South Asia; leaves open effects on current vaccine performance.
Of 731 stool specimens collected from children with diarrhea in Kathmandu, Nepal, from August 2004 through July 2005, 170 (23.3%) tested positive for rotavirus. Reverse transcription-PCR, including a revised G12-specific primer set, identified 56 (32.9%) as G2P[4] and 39 (23.0%) as G12 with P[6], P[8], or P[4].
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Pun et al. (2007) conducted a cross-sectional in Acute diarrhea (n=731). Rotavirus infection was evaluated on Detection of rotavirus and specific G12 strains. Among 731 children with acute diarrhea in Nepal, 23.3% tested positive for rotavirus, of which 23.0% were identified as the emerging G12 strain.
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