Key result
Massive catecholamine administration for 10 days in a 34-year-old man with severe septic shock was followed by extensive left ventricular calcification and deteriorating heart function.
Case Report (n=1)
No
Massive catecholamine administration for septic shock can lead to severe myocardial injury and extensive left ventricular calcification.
May signal catecholamine-related LV injury in septic shock; hypothesis-generating and does not yet change practice.
Lapatto‐Reiniluoto O, Vaalamo M, Takkunen O, Mänttäri M (Helsinki University Central Hospital, Helsinki, Finland). Left ventricular calcification following resuscitation (Case Report). J Intern Med 2000; 248: 85–87. In this paper we report a case of 34‐year‐old man with a severe septic shock. Because of profound hypotension he was given massive amounts of catecholamines for 10 days. After a short recovery the function of his heart started to deteriorate again and clear calcification around the left ventricle was disclosed by computer tomography. Catecholamines are known to induce myocardial injury resulting in a special form of cardiomyopathy with eventual calcification, but there are no previous reports of myocardial calcification to this extent.
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Lapatto‐Reiniluoto et al. (2000) conducted a case report in Severe septic shock (n=1). Catecholamines was evaluated on Left ventricular calcification. Massive catecholamine administration for 10 days in a 34-year-old man with severe septic shock was followed by extensive left ventricular calcification and deteriorating heart function.
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