Why the study?
Does the combination of relative lymphocytopenia and rapid creatine kinase-MB improve the early diagnosis of myocardial infarction in patients presenting with chest pain compared to ST-segment elevation alone?
Population
384 patients presenting to the emergency department with chest pain.
Comparison
Measurement of automated leukocyte differentials… vs Electrocardiographic ST-segment elevation.
Design
Cohort, blinded study
Follow-up
at the time of initial assessment
Authors
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May aid early MI diagnosis beyond ST elevation alone; leaves open prospective validation before practice change.
Does the combination of relative lymphocytopenia and rapid creatine kinase-MB improve the early diagnosis of myocardial infarction in patients presenting with chest pain compared to ST-segment elevation alone?
The combination of relative lymphocytopenia and elevated rapid CK-MB provides an accurate early marker of myocardial infarction that improves diagnostic sensitivity compared to ST-segment elevation alone.
Stephen P. Thomson (1995) studied this question.
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