Key result
Radiofrequency catheter ablation for AF resulted in a 2.3% incidence of pacemaker implantation at 3 months, with female sex (OR 3.08) and paroxysmal AF (OR 4.71) as independent predictors.
Why the study?
Pacemaker implantation is sometimes inevitable during or after RFCA for AF, motivating evaluation of its incidence and associated risk factors within 3 months.
What are the predictors of pacemaker implantation within 3 months after radiofrequency catheter ablation for atrial fibrillation?
Cohort (n=1,005)
No
What are the predictors of pacemaker implantation within 3 months after radiofrequency catheter ablation for atrial fibrillation?
Older age, female sex, paroxysmal AF, and repeated ablation independently predict the need for pacemaker implantation within 3 months after RFCA for atrial fibrillation.
Identified predictors of early PMI after AF ablation warrant prospective validation; leaves open their role in guiding periprocedural management.
BACKGROUND: It is inevitable for patients to have a temporary or permanent pacemaker implanted during or after radiofrequency catheter ablation (RFCA) for treatment of atrial fibrillation (AF) in some cases. The aim of our study was to evaluate the incidence of pacemaker implantation (PMI) during or within 3 months of RFCA for AF and to identify the risk factors that were associated with PMI. METHODS: We performed a retrospective analysis of consecutive AF patients who underwent RFCA between August 2018 and October 2020 at our center. The incidence of PMI within 3 months during or after RFCA were assessed. A multivariate logistic regression model was performed to identify predictors of PMI. RESULTS: One thousand and five patients (mean age, 60.2 ± 10.3 years; 37.6% women) were included in this analysis. PVI was performed in all patients. A total of 23 (2.3%) patients had a pacemaker implanted within 3 months during or after ablation. Multivariable logistic regression analysis revealed that older age (OR: 1.08 [95% CI 1.03-1.13], p = .003), female sex (OR: 3.08 [95% CI 1.28-7.45], p = .012), paroxysmal AF (OR: 4.71 [95% CI 1.09-20.45], p = .038) and repeated ablation (OR: 2.78 [95% CI 1.04-7.40], p = .041) were the independent predictors for PMI. CONCLUSIONS: Older age, female sex, paroxysmal AF and repeated ablation were identified as predictive risk factors for PMI after RFCA in patients with AF. A "watch and wait" strategy could be taken for patients with temporary PMI after ablation, especially for those with prolonged sinus pause after AF termination.
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Guo et al. (2023) conducted a cohort in Atrial fibrillation (n=1,005). Radiofrequency catheter ablation was evaluated on Pacemaker implantation within 3 months. Radiofrequency catheter ablation for AF resulted in a 2.3% incidence of pacemaker implantation at 3 months, with female sex (OR 3.08) and paroxysmal AF (OR 4.71) as independent predictors.
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