Why the study?
Does aortic valve replacement with freehand glutaraldehyde-treated autologous pericardium provide safe clinical outcomes in patients requiring valve replacement?
Does aortic valve replacement with freehand glutaraldehyde-treated autologous pericardium provide safe clinical outcomes in patients requiring valve replacement?
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Aortic valve replacement using freehand glutaraldehyde-treated autologous pericardium is a feasible technique with low hospital mortality and thrombogenicity, potentially useful for patients with a small aortic annulus.
The surgical technique of aortic valve replacement with freehand glutaraldehyde-treated autologous pericardium is described. Forty-nine patients underwent this procedure without hospital mortality and no thromboembolic episodes without anticoagulation. Three patients underwent reoperation: for infective endocarditis in two; and tear of one commissure 8 months after surgery in another. This technique because of its excellent hemodynamics and low thrombogenicity might be a valid alternative particularly in patients with a small aortic annulus.
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Durán et al. (1995) studied this question.
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