Key result
A lower psoas major muscle index was independently associated with the presence of coronary artery disease in younger males (OR 0.807).
Why the study?
Associations between the presence and severity of CAD and measurements of the psoas major muscle as assessed by MDCT were not known.
Is the psoas major muscle index associated with the presence and severity of coronary artery disease?
Cross-Sectional (n=793)
No
Is the psoas major muscle index associated with the presence and severity of coronary artery disease?
Odds Ratio: 0.807 (95% CI 0.657–0.992)
p-value: p=0.038
Psoas major muscle index assessed by MDCT may serve as a novel imaging marker for evaluating the presence and severity of CAD in non-elderly males.
Lower PMMI was associated with CAD presence/severity in non-elderly males; leaves open its added value for risk stratification on MDCT.
The associations between the presence and severity of coronary artery disease (CAD) and measurements of the psoas major muscle (PMM) as assessed by multidetector row coronary computed tomography angiography (MDCT) are not known.We enrolled 793 patients who were clinically suspected to have CAD or had at least one cardiac risk factor and had undergone MDCT. The number of significantly stenosed coronary vessels (VD) and measurements of the PMM index (PMMI) were determined using MDCT.PMMI in the CAD group was significantly lower than that in the non-CAD group in males, but not females. In addition, the levels of PMMI tended to increase as the number of VD decreased in males. When male patients were divided into 2 groups according to median value of age, that is, relatively younger (53.4 ± 9.2 years) and older (72.6 ± 5.7 years) groups, the presence of CAD was independently associated with PMMI in the younger group by a multiple logistic regression analysis. The cut-off level of PMMI that gave the greatest sensitivity and specificity for the diagnosis of CAD in younger males was 8.3 cm/m (sensitivity 0.441, specificity 0.752).In conclusion, PMMI may be an imaging marker for evaluating the presence and/or severity of CAD in males, and particularly in the non-elderly.
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Imaizumi et al. (2020) conducted a cross-sectional in Coronary artery disease (n=793). Psoas major muscle index (PMMI) vs. Higher PMMI was evaluated on Presence of coronary artery disease in younger males (OR 0.807, 95% CI 0.657-0.992, p=0.038). A lower psoas major muscle index was independently associated with the presence of coronary artery disease in younger males (OR 0.807).
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