Key result
A target-orientated algorithm for regional citrate-calcium anticoagulation showed an excellent fit to laboratory measurements across different blood hematocrit values.
A novel target-orientated algorithm for regional citrate-calcium anticoagulation successfully accounts for hematocrit and filter clearance to achieve precise ionized calcium targets in extracorporeal therapies.
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May enable tighter calcium control in extracorporeal circuits; leaves open effects on clinical outcomes and filter life.
Brandl et al. (2011) studied Extracorporeal therapies such as dialysis. Target-orientated algorithm for regional citrate-calcium anticoagulation was evaluated on Correlation between model calculations and laboratory measurements for different blood Hct values. A target-orientated algorithm for regional citrate-calcium anticoagulation showed an excellent fit to laboratory measurements across different blood hematocrit values.
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