Why the study?
Does the use of glutaraldehyde treated human umbilical veins maintain graft patency compared to autogenous jugular veins in a canine femoral artery bypass model?
Population
15 dogs undergoing femoral artery bypass
Comparison
Glutaraldehyde treated human umbilical veins to… vs Autogenous jugular veins placed in the…
Design
Preclinical
Follow-up
four months
Authors
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Animal results caution against clinical translation of umbilical vein grafts; leaves open need for optimization in future studies.
Does the use of glutaraldehyde treated human umbilical veins maintain graft patency compared to autogenous jugular veins in a canine femoral artery bypass model?
In a canine model, human umbilical vein grafts showed a prohibitively high incidence of neointimal fibrous hyperplasia and thrombosis compared to autogenous veins.
Oblath et al. (1978) studied this question.
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