Key result
Cryo-electron microscopy revealed the structure of the mammalian skeletal muscle actomyosin rigour complex at 5.2 Å resolution, showing a large conformational change that opens the nucleotide-binding pocket.
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Atomic-resolution skeletal actomyosin structure refines contraction models; leaves open cardiac myosin applications pending validation.
Fujii et al. (2017) studied Actomyosin rigour complex. Cryo-electron microscopy was evaluated on 3D density map and structure of the actomyosin rigour complex. Cryo-electron microscopy revealed the structure of the mammalian skeletal muscle actomyosin rigour complex at 5.2 Å resolution, showing a large conformational change that opens the nucleotide-binding pocket.
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