The study highlights site-specific differences in resistin gene expression in adipose tissue among obese patients with and without type 2 diabetes.
Adipose resistin patterns merit targeted mechanistic study in T2DM; cross-sectional data leave causal role open and should not change practice.
Background: This study demonstrated site-specific adipose tissue resistin gene expression differences in individuals with and without type 2 diabetes mellitus. The relationship between conventional drug therapy and adipose tissue resistin gene expression was also determined. Paired omental and subcutaneous adipose tissues were excised during elective surgery from morbidly obese and obese patients.
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A 2013 study studied this question.
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