September 1, 1990Archives of Internal Medicine
Angiotensin-Converting Enzyme Inhibitors in Congestive Heart Failure
Population
Patients with mild, moderate, and severe congestive heart failure, and selected patients after myocardial…
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
May support ACE inhibitor use in selected HF patients; leaves open optimal dosing and integration with contemporary therapies.
Structured PICO
P
Population
Patients with mild, moderate, and severe congestive heart failure (CHF), and selected patients after myocardial infarction.
I
Intervention
Angiotensin-converting enzyme (ACE) inhibitors (including captopril, enalapril maleate, and lisinopril), alone or in combination with diuretics and digoxin.
ACE inhibitors are an effective treatment for congestive heart failure, improving hemodynamics, quality of life, and survival, though pharmacokinetic differences influence the risk of symptomatic hypotension.
Cite This Study
Prakash Deedwania (1990) studied this question.