This is the first reported case of hepatitis and encephalitis secondary to Coxsackie virus type A9 in an adult, demonstrating that complete recovery can occur without specific treatment.
Complete recovery without treatment seen in novel adult Coxsackie A9 hepatitis-encephalitis; leaves open generalizability and need for prospective data.
Coxsackie virus infection most commonly manifests itself in the neonatal period as a multisystem disease. This life-threatening neonatal infection has been recently treated with a new anti-picornaviral drug, pleconaril. In contrast, in adults Coxsackie virus is an uncommon source of hepatitis, but Coxsackie virus type B has been described in case reports to cause hepatitis. This is the first case report of hepatitis and encephalitis secondary to Coxsackie virus type A9 in an adult. This virus was found in a culture of the cerebrospinal fluid and was confirmed by PCR. The patient recovered completely without specific treatment.
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Moreau et al. (2011) studied this question.
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