Population
Nucleotide and protein sequences obtained from 32 original clinical samples, 8 enterovirus isolates, and 64…
Comparison
Sequence analysis of the VP1 genomic region… vs Pairwise sequence alignment methods.
Design
Preclinical
Authors
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Phylogenetic methods may improve enterovirus typing accuracy in labs; leaves open validation before clinical adoption.
Phylogenetic inference and the freely available Clustal W multiple-sequence alignment program outperform commercial pairwise alignment packages for the molecular typing of enteroviruses using the VP1 region.
Palacios et al. (2002) studied this question.
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