Why the study?
Post-switch cVDPV2 outbreaks exceeded forecasts trending toward zero, with new outbreaks seeded by mOPV2 use, prompting an update on global cVDPV outbreaks.
Population
33 cVDPV outbreaks worldwide
Design
Epidemiologic surveillance report
Authors
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Continued cVDPV surveillance is essential in low-immunity areas; leaves open optimal mOPV2 deployment strategies.
The number and geographic breadth of post-switch cVDPV2 outbreaks have exceeded forecasts, highlighting the need for novel OPV type 2 (nOPV2) to limit new emergences.
Alleman et al. (2020) studied this question.
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