December 11, 2014PLoS ONEOpen Access

An Outbreak of Type Π Vaccine-Derived Poliovirus in Sichuan Province, China: Emergence and Circulation in an Under-Immunized Population

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Population

Children in Ngawa County, Sichuan Province, China, including 1 clinical compatible polio case and 3 VDPV…

Design

Other

Authors

HWHaibo WangXinyang Normal University GFGang FangIcahn School of Medicine at Mount Sinai WYWenzhou YuChinese Center For Disease Control and Prevention

Discussion

Member takes

Implication

Outbreak data support high immunization coverage to limit cVDPV; leaves open optimal SIA strategies in under-vaccinated regions.

Structured PICO

Population

Children (0.8-1 years old) in Ngawa County, Sichuan Province, China, including 1 clinical compatible polio case and 3 VDPV cases among 7 acute flaccid paralysis cases reported in 2011.

Intervention

Field investigation, genetic sequencing of poliovirus capsid protein VP1, coverage survey, and supplementary immunization activities (SIAs).

Outcome

Viral propagation and genetic characterization of outbreak isolates.

An outbreak of type II circulating vaccine-derived poliovirus in an under-immunized population in China highlights the need for high routine immunization coverage and targeted supplementary immunization activities.

Cite This Study

Wang et al. (2014) studied this question.

synapsesocial.com/papers/6a906f77b71d06dae589e75e https://doi.org/10.1371/journal.pone.0113880

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An Outbreak of Type Π Vaccine-Derived Poliovirus in Sichuan Province, China: Emergence and Circulation in an Under-Immunized Population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

An Outbreak of Type Π Vaccine-Derived Poliovirus in Sichuan Province, China: Emergence and Circulation in an Under-Immunized Population

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider