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October 7, 2010HeartOpen Access

Prevalence and impact of a chronic total occlusion in a non-infarct-related artery on long-term mortality in diabetic patients with ST elevation myocardial infarction

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Why the study?

Does the presence of a CTO in a non-infarct-related artery increase 5-year mortality in diabetic patients presenting with STEMI?

Population

4,506 patients with ST elevation myocardial infarction treated with primary percutaneous coronary…

Comparison

Presence of a chronic total occlusion in a… vs Single vessel disease or multivessel disease…

Design

Cohort

Follow-up

5 years

Authors

BCBimmer E. ClaessenLHLoes HoebersRSRené J. van der Schaaf

Discussion

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Member takes

Overview

May identify higher-risk diabetic STEMI patients; hypothesis-generating and requires prospective trials before changing practice.

Structured PICO

Does the presence of a CTO in a non-infarct-related artery increase 5-year mortality in diabetic patients presenting with STEMI?

P
Population
4,506 patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI), including 539 (12%) with diabetes mellitus (DM).
I
Intervention
Presence of a chronic total occlusion (CTO) in a non-infarct-related artery (non-IRA)
C
Comparator
Single vessel disease (SVD) or multivessel disease (MVD) without a CTO
O
Outcome
5-year mortalityhard clinical

In diabetic patients with STEMI, multivessel disease carries significant prognostic implications primarily when a concurrent chronic total occlusion is present in a non-infarct-related artery.

Cite This Study

Claessen et al. (2010) studied this question.

synapsesocial.com/papers/6a90702da9a6d70ff18a5316https://doi.org/10.1136/hrt.2010.197673
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