Why the study?
Does the presence of chronic total occlusion (CTO) increase long-term mortality in STEMI patients treated with primary PCI?
Population
836 STEMI patients treated with primary percutaneous coronary intervention (PCI)
Comparison
Presence of chronic total occlusion (CTO) vs Absence of CTO (non-CTO group)
Design
Cohort
Follow-up
6 years
Key result
The presence of a chronic total occlusion independently predicted long-term mortality (OR 2.07) in STEMI patients treated with primary PCI.
Authors
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CTO presence may inform risk stratification in STEMI; leaves open whether revascularization improves survival.
Cohort (n=836)
No
Does the presence of chronic total occlusion (CTO) increase long-term mortality in STEMI patients treated with primary PCI?
Effect estimate: OR 2.07 (95% CI 1.30-3.28)
Absolute Event Rate: 38.6% vs 25.4%
p-value: p=0.002
The presence of a chronic total occlusion is an independent predictor of long-term mortality in STEMI patients undergoing primary PCI.
Lesiak et al. (2016) conducted a cohort in acute ST-segment elevation myocardial infarction (STEMI) (n=836). Presence of chronic total occlusion (CTO) vs. Absence of chronic total occlusion (non-CTO) was evaluated on 6-year all-cause mortality (OR 2.07, 95% CI 1.30-3.28, p=0.002). The presence of a chronic total occlusion independently predicted long-term mortality (OR 2.07) in STEMI patients treated with primary PCI.